Vagina As A Rare Site Of Extragonadal Endodermal Sinus Tumour

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Endodermal Sinus Tumor of Vagina in Infants

Endodermal sinus tumor (or Yolk Sac tumor) of the vagina is a rare malignant germcell tumor which is seen exclusively in children younger than 3 years of age. We report two cases of endodermal sinus tumor of the vagina. In both cases no radiological investigation was done and serum alpha-fetoprotein was elevated. The histopathological examination of both the tumor masses revealed vaginal endode...

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Endodermal sinus tumor of the vagina in a child.

Malignant germ cell tumors are rare tumors of the childhood accounting for less than 3 % of pediatric malignancies. Endodermal sinus tumor (EST) is the most common histologic subtype of malignant GCT. The vagina is an extremely rare site for GCTs [1]. They are usually diagnosed before 3 years of age. Historically, the approach to therapy has included radical surgical resection with adjuvant irr...

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Endodermal sinus tumor of the vagina--a rare entity treated exclusively with chemotherapy.

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In a female child presenting with vaginal bleeding or a mass protruding through the vagina, it is mandatory to perform an endoscopic and laparoscopic examination and biopsy to establish the correct diagnosis and precise extent of the lesion. An endodermal sinus tumor (EST) of the vagina is a rare, malignant germ cell tumor that occurs primarily in infants. Clearly, the vagina is a critical site...

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ژورنال

عنوان ژورنال: Pediatric Hematology Oncology Journal

سال: 2018

ISSN: 2468-1245

DOI: 10.1016/j.phoj.2018.11.158